What is the antidote for amiodarone infiltration?

Conclusion: Administration of intradermal hyaluronidase after amiodarone extravasation was associated with decreased expansion of erythema and warmth as well as an improvement in patient-reported pain scores without any noted adverse effects.

Is amiodarone an extravasation?

However, extravasation is not uncommon with peripheral vein infusions and care should be taken to minimise the risk of tissue necrosis by only administering amiodarone infusions via a central vein. ​

How is vancomycin infiltration treated?

Vancomycin extravasation was successfully managed by utilizing cold compress for the first 24 hours post-extravasation with common gauze open dressings and silver sulfadiazine 1% until the wound was healed.

Is there an antidote for amiodarone?

No specific antidote for amiodarone toxicity is available, and amiodarone is not dialyzable.

What side effects does amiodarone have?

More common

  • Cough.
  • dizziness, lightheadedness, or fainting.
  • fever (slight)
  • numbness or tingling in the fingers or toes.
  • painful breathing.
  • sensitivity of the skin to sunlight.
  • trembling or shaking of the hands.
  • trouble with walking.

Can amiodarone be stopped suddenly?

Your doctor may decrease your dose during your treatment if you develop side effects. Follow your doctor’s directions carefully. Do not stop taking amiodarone without talking to your doctor. You may need to be closely monitored or even hospitalized when you stop taking amiodarone.

How to treat infiltrated IV?

Your clinician will likely do the following: Stop the infusion Remove the IV Mark the outline affected area with a marker Photograph the affected area Apply a hot or cold compress based on the type of IV fluid infiltrated Elevate the extremity Inject medication into the subcutaneous tissue

How to treat IV infiltration?

Use cold or heat packs as directed. Your healthcare provider will tell you which to use according to the type of infiltrated fluid. Rest and elevate your arm above the level of your heart as directed . This will help decrease swelling and pain. Prop your arm on pillows or blankets to keep it elevated comfortably.

Is amiodarone a vesicant?

Amiodarone IV should be administered via a Central Venous Catheter. It has a pH of 4.08. If administered outside of the standard concentration of 900 mg/500mL it should be administered using a 0.22 micron filter to prevent preciptiate from reaching the patient. Amiodarone IV is a known vesicant.