What is incomplete intestinal metaplasia?
Intestinal metaplasia (IM) as precancerous lesion is either partial or complete transformation of gastric glands epithelial cells into the intestinal type. It may appear either in antrum or pylorus mucosa or diffusely.
Can gastric intestinal metaplasia be reversed?
In the long term, with follow up of at least five years, there is epidemiological evidence that IM may be reversible although a combination of antioxidant agents and eradication of H pylori may be necessary to achieve this.
How often does intestinal metaplasia turn into cancer?
Intestinal metaplasia (IM) is recognized as a precancerous lesion for gastric cancer, increasing the risk by 6-fold. IM is highly prevalent in the general population, being detected in nearly 1 of every 4 patients undergoing upper endoscopy.
What percentage of intestinal metaplasia becomes cancer?
A total of 1055 patients were identified with GIM; 6 (0.6%) developed either dysplasia or gastric cancer.
What is the treatment for intestinal metaplasia?
After confirming a diagnosis of intestinal metaplasia, the doctor can begin treatment. Currently, the most effective treatment is to remove the H. pylori infection completely. This removal is done in combination with the use of antioxidant agents.
How do you get rid of intestinal metaplasia?
How do you treat intestinal metaplasia naturally?
Some dietary practices are believed to help in the prevention and treatment of intestinal metaplasia. These include eating lots of plant-based foods such as fresh fruits and vegetables because they are full of antioxidants. Antioxidants include vitamin C, vitamin E, flavonoids, carotenoids, and phenols.
What are the stages of intestinal metaplasia?
The development of gastric adenocarcinoma of the intestinal type is thought to progress sequentially through four stages: nonatrophic gastritis, multifocal atrophic gastritis, IM, and dysplasia.
What is the best treatment for intestinal metaplasia?
Currently, the most effective treatment is to remove the H. pylori infection completely. This removal is done in combination with the use of antioxidant agents. Studies have shown this to be an effective way of trying to reverse intestinal metaplasia.
How to treat intestinal metaplasia of the stomach reversible?
In an Italian study, co-administration of ascorbic acid with H pylori eradication significantly resolved IM of the gastric mucosa, and the authors concluded that chemoprevention treatment should be considered. 21 “Co-administration of ascorbic acid with H pylori eradication significantly resolved IM of the gastric mucosa”
What are the different types of intestinal metaplasia?
BACKGROUND/AIMS Intestinal metaplasia (IM) is a common finding at the oesophagogastric junction, but the aetiopathogenesis of the different IM subtypes—that is, incomplete IM (specialised columnar epithelium, SCE) and complete IM— and their associations with gastro-oesophageal reflux disease and Helicobacter pylori gastritis are unclear.
What to do after a gastric metaplasia diagnosis?
Purpose of review: One of the most vexing problems for gastroenterologists is what actions to take after receiving a histological diagnosis of gastric intestinal metaplasia.
How is gastric metaplasia related to carcinogenesis?
Summary: Gastric intestinal metaplasia is a potential reversible product of injury and repair and not directly connected with carcinogenesis. Intestinal metaplasia is a biomarker for prior gastric injury and repair. The risk of gastric cancer is best assessed in relation to the severity, extent, and, most importantly,