Is bronchiectasis non-cystic fibrosis?

Bronchiectasis is sometimes called non-cystic fibrosis bronchiectasis. This is because there is a different condition called cystic fibrosis. People who have cystic fibrosis can have lung symptoms similar to those of bronchiectasis, but the treatments and outlook are different.

How common is non-cystic fibrosis bronchiectasis?

The incidence of non-cystic fibrosis bronchiectasis is 2–5 patients per 1,000 population. It is more common in the elderly and older, frailer patients tend to have a more severe and symptomatic disease. In one study of over 1,200 patients with bronchiectasis, 50% were over 65 years old and 19.1% were over 75 years.

What causes non CF bronchiectasis?

Bronchiectasis may be caused by several factors, including previous severe respiratory infections (e.g., bacterial pneumonia or tuberculosis), allergic bronchopulmonary aspergillosis (ABPA), impairment of ciliary clearance (e.g., primary ciliary dyskinesia), and primary or secondary immunodeficiency, and it may also be …

What is the prognosis for bronchiectasis?

Most people diagnosed with bronchiectasis have a normal life expectancy with treatment tailored to their needs. Some adults with bronchiectasis developed symptoms when they were children and live with bronchiectasis for many years. Some people, who have very severe bronchiectasis, may have a shorter life expectancy.

What are the causes of bronchiectasis?

What causes bronchiectasis?

  • Cystic fibrosis (leads to nearly 50 of every 100 cases in the U.S.)
  • Severe pneumonia infection.
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma.
  • Whooping cough or measles.
  • Tuberculosis.
  • Fungal infections.
  • Immunodeficiency disorders.

How does cystic fibrosis cause bronchiectasis?

Cystic fibrosis is one of the leading causes of bronchiectasis, a chronic lung condition with abnormal widening and scarring of the airways (bronchial tubes). This makes it harder to move air in and out of the lungs and clear mucus from the bronchial tubes.

What are the causes of non CF bronchiectasis?

For non-CF bronchiectasis, the cause is not always known. This is called idiopathic bronchiectasis. However, in other cases, causes include: Genetic diseases like primary ciliary dyskinesia or alpha-1 antitrypsin deficiency

Are there any options for treatment of bronchiectasis?

Bronchiectasis. Medications to dilate the airways may be useful in some, but the evidence is not very good. The use of inhaled steroids has not been found to be useful. Surgery, while commonly done, has not been well studied. Lung transplantation may be an option in those with very severe disease.

How does bronchiectasis prevent germs from entering lungs?

Bronchiectasis describes the widening (“ectasis”) of some of the airways. The airways normally produce a small amount of mucus (sputum or phlegm) which traps any germs that enter the lungs. This mucus is then carried up to the throat by tiny hairs on the cells lining the airways, known as cilia, to prevent infection.

How does NTM related bronchiectasis affect the host?

There is mounting evidence that patients with NTM-related bronchiectasis have a distinct immunologic phenotype that results in an imbalance of cytokines leading to inability of the host to resist mycobacterial infection ( 20, 21 ).