What does apparent diffusion coefficient mean on MRI?

Apparent diffusion coefficient (ADC) is a measure of the magnitude of diffusion (of water molecules) within tissue, and is commonly clinically calculated using MRI with diffusion-weighted imaging (DWI) 1.

What does restricted diffusion mean on MRI?

Restricted diffusion is seen as high-signal intensity on DWI with corresponding reduced apparent diffusion coefficient (ADC) values. ADC is a measurement of the diffusion of water molecules in a given tissue.

What is B value in diffusion?

b = γ² G² δ² (Δ−δ/3) The b-value depends on the strength, duration, and spacing of these pulsed gradients. A larger b-value is achieved with increasing the gradient amplitude and duration and by widening the interval between gradient pulses.

What is B value in diffusion weighted imaging?

Conclusion: In DWI, the optimal b value is 600 s/mm(2) ; multiple b values of 600 s/mm(2) and higher are recommended to differentiate between benign and malignant abdominal lesions.

What does ADC mean on a prostate MRI?

To determine the utility of apparent diffusion coefficient (ADC) values in differentiation of prostate cancer from normal prostate parenchyma and prostatitis we obtained ADC values of 50 patients at b 100, 600 and 1,000 s/mm2 diffusion gradients.

How do you calculate the B-value of an earthquake?

b1 value estimation using the maximum likelihood estimation. Probability density function for the estimation of b1 value is adopted based on the exponential part of fm(m) in Equation (5) as follows : fm(m)={βe−β(m−m0)1−e−β(mmax−m0−Δm2)11+Cm0

What is B-value in research?

We describe the use of the B-value, which is a transformed Z-value, for the calculation of conditional power. In data monitoring, interim Z-values do not allow simple projections to the end of the study. Moreover, because of their popular association with P-values, Z-values are often misinterpreted.

What is T2 shine through?

T2 shine-through refers to high signal on DWI images that is not due to restricted diffusion, but rather to high T2 signal which ‘shines through’ to the DWI image. T2 shine through occurs because of long T2 decay time in some normal tissue.